Somatostatin-Like Immunoreactivity in Rat Blood
نویسندگان
چکیده
منابع مشابه
Tumor and plasma somatostatin-like immunoreactivity in transplantable rat medullary thyroid carcinoma.
We have recently reported the establishment of 16 series of calcitonin-producing transplantable rat medullary thyroid carcinoma. In the present study, these tumor series have been evaluated for the presence of somatostatin-like immunoreactivity. Each of the series contained detectable levels of both peptides. Immunoreactive somatostatin varied from less than 1 ng/mg of protein to almost 500 ng/...
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Neural crest cells are the embryonic progenitors of several adult cell types, including some neurons that contain the neuroactive peptide somatostatin. To begin to understand the control of peptide expression during neuronal ontogeny, we have investigated the development of somatostatin-like immunoreactivity (SLI) in embryonic quail paravertebral sympathetic ganglia in vivo. SLI was identified ...
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Selective neurotoxins have been of value in providing a means for specifically interfering with the actions of endogenous neurotransmitter candidates. Others have shown cysteamine (CSH) to deplete the gastrointestinal tract and hypothalamus of rats of immunoreactive somatostatin, suggesting a toxic action of that compound directed against somatostatin-containing cells. The present study further...
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Large differences in retinal concentration of somatostatin-like immunoreactivity (SLI) were observed even among closely related species. Hog and chicken retinas, like those of goldfish and frog described previously, contained roughly equal amounts of SLI coeluting with somatostatin tetradecapeptide (S14) and octacosapeptide (S28) on Sephadex G 50 chromatography. In contrast, virtually all of th...
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The distribution and morphology of neurons containing somatostatin (SOM) was investigated in the amygdala (CA) of the pig. The SOM-immunoreactive (SOM-IR) cell bodies and fibres were present in all subdivisions of the porcine CA, however, their number and density varied depending on the nucleus studied. The highest density of SOM-positive somata was observed in the layer III of the cortical nuc...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1978
ISSN: 0021-9738
DOI: 10.1172/jci109059